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目的观察醒脑静注射液联合吡拉西坦治疗急性脑梗死的临床效果。方法急性脑梗死患者90例,随机均分为两组,分别采用吡拉西坦治疗(对照组)和醒脑静联合吡拉西坦治疗(试验组)。治疗方法:吡拉西坦100ml,静脉输注,每天2次;醒脑静注射液20 ml,加入生理盐水250 ml,静脉输注,每天1次;10d为1个疗程。比较两组疗效。结果两组患者治疗后的神经缺损评分均较治疗前降低(P<0.05),试验组的改善程度优于对照组[(13.88±5.33)分vs.(20.85±6.13)分](P<0.05)。治疗1个疗程后,试验组总有效率和显效率优于对照组(91.11%vs.66.67%和68.89%vs.48.89%)(P<0.05)。结论醒脑静注射液联合吡拉西坦较单用吡拉西坦治疗急性脑梗死患者更能有效改善神经功能。
Objective To observe the clinical effects of xingnaojing injection combined with piracetam on acute cerebral infarction. Methods 90 patients with acute cerebral infarction were randomly divided into two groups, treated with piracetam (control group) and xingnaojing combined with piracetam (experimental group). Treatment: Piracetam 100ml, intravenous infusion, 2 times a day; Xingnaojing injection 20 ml, adding saline 250 ml, intravenous infusion, 1 day; 10d for a course of treatment. Compare the two groups curative effect. Results The scores of neurological deficits after treatment in both groups were significantly lower than those before treatment (P <0.05). The improvement in the experimental group was better than that in the control group [(13.88 ± 5.33) vs. (20.85 ± 6.13) ). After a course of treatment, the total effective rate and markedly effective rate in the experimental group were superior to those in the control group (91.11% vs.66.67% and 68.89% vs.48.89%, respectively) (P <0.05). Conclusion Xingnaojing injection combined with piracetam is more effective in improving neurological function than piracetam alone in patients with acute cerebral infarction.