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目的:探讨罗哌卡因配伍小剂量芬太尼用于硬膜外分娩镇痛对妊娠妇女和胎儿的影响。方法:观察进行分娩镇痛与未进行分娩镇痛各490例产妇的镇痛效果、产程时间、缩宫素使用情况、分娩方式、产后出血量以及新生儿情况。结果:两组产后出血、新生儿窒息差异无统计学意义,而镇痛组的缩宫素使用量增多、活跃期较对照组缩短,疼痛程度和焦虑情绪比对照组明显减轻,差异有统计学意义(P<0.05)。结论:低浓度罗哌卡因配伍小剂量芬太尼用于硬膜外分娩镇痛安全有效,能加速活跃期,满足整个产程的镇痛需要,无运动阻滞,对母婴均无不良影响。
Objective: To investigate the effect of ropivacaine combined with small dose of fentanyl on pregnant women and fetus during epidural analgesia. Methods: The analgesic effect, labor duration, oxytocin use, mode of delivery, postpartum hemorrhage, and neonatal status were observed in 490 maternal women who received labor analgesia and did not perform childbirth analgesia. Results: The postpartum hemorrhage and neonatal asphyxia had no significant difference between the two groups, but the use of oxytocin increased in the analgesic group, the active phase was shorter than the control group, the degree of pain and anxiety were significantly relieved compared with the control group, the difference was statistically significant Significance (P <0.05). Conclusion: Low concentration of ropivacaine combined with low dose of fentanyl for epidural analgesia is safe and effective, can accelerate the active phase, to meet the needs of the entire labor analgesia, no motor block, no adverse effects on mother and child .