PI3K/Akt pathway is involved in the activation of RAW 264.7 cells induced by hydroxypropyltrimethyl

• 作 者: YANG Yue XING Rong’e LIU Song
• 机 构: KeyLaboratoryofExperimentalMarineBiology,LaboratoryforMarineDrugsandBioproductsofQingdaoNationalLabo
• 出 处: 海洋湖沼学报(英文)
• 发表日期: 2020年3期
• 关键词: hydroxypropyltrimethyl AMMONIUM chloride CHITOSAN RAW 264.7 CELLS PI3K/Akt pathw
• 基金项目: Supported by the National Key R&D Program of China(No.2018YFC0311305),the Key Research and Development Program of Shandong Province(Nos.2019GHY112015,2019YYSP028)

We previously demonstrated that 2-hydroxypropyltrimethyl ammonium chloride chitosan(HACC)promoted the production of nitric oxide(NO)and proinflammatory cytokines by activating the mitogen-activated protein kinases(MAPK)and Janus kinase(JAK)/STAT pathways