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我补充谈几个有关哮喘治疗的问题: 一、肥大细胞膜稳定剂肥大细胞膜稳定剂应算是一类病因治疗性药物,色甘酸二纳(DSCG)是这类药物中最早问世的品种,通常需以其干粉或2%水悬液喷雾吸入。我省金坛县制药厂生产的敏喘宁(丙氧苯氮嘌呤酮、M&B22948)作用强于DSCG,且口服可以取效,甚为方便。国外尚有硫蒽四唑(Doxantra-zole)和噻哌酮(甲哌噻庚酮、Ketotifen)等口服药品,特别是噻哌酮颇受重视,它的作用比DSCG和敏喘宁都强得多,成人剂量1～2mg/日”它不仅能稳定肥大细胞、抑制介质释放和抑制磷酸二酯酶的活性,兼能降低支气管的高反应性,直接拮抗组胺和慢反应物质促使支气管平滑肌收缩的效应,据报导总有效率达85%(其中显效率65%)。它对运动性哮喘、药物性
I will add a few talk about the treatment of asthma problems: First, the mast cell membrane stabilizer Mast cell membrane stabilizer should be considered a class of cause of the therapeutic drugs, cromolyn mellitus (DSCG) is the first of these drugs come out of the species, usually with Its dry powder or 2% aqueous suspension spray inhalation. Mintan Pharmaceutical Factory in our province production Minmin Ning (Propoxyphenyl arsenazone, M & B22948) stronger than the role of DSCG, and oral can take effect, is very convenient. There are foreign countries such as Doxantrazole (Doxantra-zole) and ketoprofen (ketoprofen, Ketotifen) and other oral drugs, especially the importance of thiophene ketone, its role than DSCG and Min asthma are much stronger , Adult dose of 1 ~ 2mg / day "It not only stabilize mast cells, inhibit the release of media and inhibit phosphodiesterase activity, and can reduce bronchial hyperresponsiveness, direct antagonism of histamine and slow response substance to promote bronchial smooth muscle contraction Effect, it was reported that the total effective rate of 85% (65% of which was markedly effective.) It is the exercise of asthma, drug-induced