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登革病毒主要通过埃及伊蚊和白纹伊蚊叮咬传播,但由于登革热流行区媒介伊蚊广泛存在,一般很难区分登革热病例的感染是否因蚊虫叮咬所致,从而对感染途径不确定的病例最后也归咎于蚊虫叮咬所致.目前非蚊媒途径传播登革病毒已在多个国家证实和报道,感染途径包括母婴垂直传播、输血传播、器官移植传播和职业暴露传播等,非蚊媒叮咬传播登革病毒的风险是存在的,但因证实较困难,人类自身免疫力和多数感染为无症状带毒者等原因而被低估.“,”The major transmission pathway of dengue virus (DENV) occurs by the bite of mosquitoes,usually Aedes aegypti and Aedes albopictus.However,some infected cases with uncertain transmission pathway were usually attributed to the bite of mosquitoes in endemic areas because of the ubiquity of Aedes.Cases of non-vector DENV transmission have been reported in the literature involving many routes including vertical transmission,transfusion related transmission,transplantation related transmission,and occupational exposure transmission.Therefore,the risk of non-vector DENV transmission might be underestimated owing to some facts,including immunity of people,high-proportion of asymptomatic cases,and unconfirmed modes of transmission.