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目的探讨阿奇霉素联合红霉素治疗小儿支原体肺炎的临床疗效。方法选取天津市津南区八里台镇卫生院2013年9月—2015年8月治疗的支原体肺炎患儿70例,按照随机数字表法分为对照组和观察组,各35例。对照组患儿给予红霉素治疗,观察组患儿给予阿奇霉素联合红霉素治疗。比较两组患儿的临床疗效、体温恢复正常时间、咳嗽消失时间及痰液消失时间,并观察患儿不良反应发生情况。结果观察组患儿治疗总有效率高于对照组(P<0.05)。观察组患儿体温恢复正常时间、咳嗽消失时间、痰液消失时间短于对照组(P<0.05)。两组患儿治疗期间均未出现明显不良反应。结论阿奇霉素联合红霉素治疗小儿支原体肺炎临床疗效确切,可有效改善患儿的临床症状及体征,缩短治疗时间,且安全性好。
Objective To investigate the clinical efficacy of azithromycin combined with erythromycin in the treatment of children with mycoplasma pneumonia. Methods Seventy patients with Mycoplasma pneumonia who were treated in Balizitang Hospital of Jinli District, Tianjin from September 2013 to August 2015 were divided into control group and observation group according to the random number table method, 35 cases each. Control group of children given erythromycin treatment, observation group of children given azithromycin combined with erythromycin treatment. The clinical curative effect, body temperature recovery time, disappearance of cough and sputum disappearance time were compared between the two groups, and the incidence of adverse reactions in children was observed. Results The total effective rate of observation group was higher than that of control group (P <0.05). In the observation group, the body temperature returned to normal, the disappearance of cough and the disappearance time of sputum were shorter than those in the control group (P <0.05). No significant adverse reactions occurred in both groups during treatment. Conclusion Azithromycin combined with erythromycin in children with mycoplasma pneumonia clinical curative effect is exact, can effectively improve children’s clinical symptoms and signs, shorten the treatment time, and good safety.