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韩国一项新的研究表明,相比于那些对药物反应良好的患者,存在阿司匹林抵抗的患者可能更容易患有严重卒中。这项研究纳入310例症状发作在48小时内的缺血性卒中或短暂性脑缺血发作患者,所有患者卒中发作前都在服用阿司匹林,其中86例(27.7%)有阿司匹林抵抗。结果显示,阿司匹林抵抗组患者更易患卒中。研究者表示,抗血小板药物如阿司匹林,可以减少血小板聚集、血栓形成,以及血栓栓塞的体积和频率。阿司匹林抵抗者,由于血小板抑制不足,而更易产生大的血栓,血栓栓塞形成率也更高,因此易出现更大面积及更严
A new study in South Korea shows that aspirin-resistant patients may be more likely to have severe strokes than those who respond well to drugs. The study enrolled 310 patients with ischemic stroke or transient ischemic attack within 48 hours of onset of symptoms. All patients took aspirin before the onset of stroke, and 86 (27.7%) had aspirin resistance. The results showed that aspirin patients were more susceptible to stroke. The researchers said that anti-platelet drugs such as aspirin, can reduce platelet aggregation, thrombosis, and thromboembolism volume and frequency. Aspirin-resistant patients, due to inadequate platelet inhibition, and more prone to large thrombus, thromboembolic rate is also higher, so prone to larger areas and more stringent