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嗜酸性淋巴肉芽肿是病原不明的疾病,好发生在耳旁软组织,并形成肿块,局部搔痒,全身发疹,外周血嗜酸性粒细胞增多,血内 IgE 水平增高。本文结合临床用光镜、电镜、免疫组化方法研究30例活检。组织学淋巴细胞返幼增生,形成多数滤泡、毛细血管增生,组织内嗜酸性粒细胞明显浸润。IgG、IgA、IgM、IgE 见淋巴细胞和嗜酸性细胞发出黄绿色荧光,组织内肥大细胞增生明显,电镜观察组织内嗜酸性粒细胞有明显的脱颗粒现象,认为本病是对某种因子进入体内引起的全身免疫性疾病,属混合型。局部表现变态反应性肉芽肿形成。
Acidophilic lymphogranuloma is a pathogen unknown disease, occurs in the soft tissue of the ear, and the formation of lumps, local itching, systemic rash, peripheral blood eosinophilia, increased blood levels of IgE. In this paper, clinical light microscopy, electron microscopy, immunohistochemical methods to study 30 cases of biopsy. Histologically, lymphocytes proliferated and proliferated to form the majority of follicles, capillary proliferation and eosinophilic infiltration in the tissues. IgG, IgA, IgM, IgE see yellowish green fluorescence of lymphocytes and eosinophils, mast cell proliferation significantly, electron microscopy of tissue eosinophils obvious degranulation, that the disease is a factor into Body caused by systemic immune disease, is a mixed type. Local manifestations of allergic granuloma formation.