论文部分内容阅读
金属离子广泛存在于自然界中,一些离子如Cu2+、Fe3+、Al3+等在生命过程中有着重要作用,而另一些离子如Hg2+、Pb2+等重金属离子即使在低浓度时也会对环境和生物体具有极强的毒性,故高选择性和高灵敏度的离子检测的研究意义重大。荧光分子探针在表达分子间识别行为以及复杂的环境、生命体系的内状态信息方面具有优异的性能,已被广泛深入地用于构建新型功能性探针分子。本文综述了近年来基于若丹明的金属阳离子如Hg2+、Cu2+、Fe3+等荧光分子探针的研究进展,包括探针的结构特征、检测机理、检测水平,更重要的是其在环境检测、生物成像、分子器件等方面的新应用,并对荧光探针所面临的问题和发展前景作了分析。
Metal ions are widely found in nature. Some ions such as Cu2 +, Fe3 +, Al3 + etc. play an important role in the life process, while other ions such as Hg2 +, Pb2 + and other heavy metal ions have very low levels of environmental and biological Strong toxicity, so the high selectivity and high sensitivity of ion detection research is significant. Fluorescent molecular probes have been used extensively in the construction of novel functional probe molecules for their excellent performance in the expression of intermolecular recognition behavior and in complex environments and in vivo state information of life systems. In this paper, the progress of rhodamine-based fluorescent metal probes based on rhodamine such as Hg2 +, Cu2 +, Fe3 + is summarized in this paper, including the structural characteristics, detection mechanism and detection level of probes. More importantly, Imaging, molecular devices and other new applications, and the problems faced by the fluorescent probes and prospects for development are analyzed.