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目的:分析前列地尔注射液对急性脑梗死患者的疗效及对纤维蛋白原水平的影响。方法:将2013年1月至2015年10月在黔南州人民医院接受治疗的74例急性脑梗死患者作为研究对象,采用双盲法将患者纳入观察组与对照组(n=37)。两组患者均实施常规治疗,观察组在此基础上采用前列地尔注射液联合治疗,比较两组患者的临床治疗效果以及纤维蛋白原水平转变情况。结果:两组患者治疗后纤维蛋白原水平均显著降低,观察组患者的下降效果更加显著,差异具有统计学意义(P<0.05)。观察组患者治疗总有效率为97.3%,显著高于对照组患者的83.78%,差异具有统计学意义(P<0.05)。结论:前列地尔注射液在急性脑梗死患者临床治疗中的应用,有助于快速降低患者的纤维蛋白原水平,提升患者临床治疗总有效率。
Objective: To analyze the curative effect of alprostinil injection on patients with acute cerebral infarction and its effect on fibrinogen level. Methods: A total of 74 patients with acute cerebral infarction who were treated in Qiannan People’s Hospital from January 2013 to October 2015 were enrolled in this study. Patients were divided into observation group and control group by double-blind method (n = 37). The two groups of patients were treated with conventional therapy. The observation group was treated with alprostadil injection on the basis of the above results, and the clinical effects and level of fibrinogen were compared between the two groups. Results: The levels of fibrinogen in both groups were significantly decreased after treatment, and the decline in the observation group was more significant (P <0.05). The total effective rate of observation group was 97.3%, significantly higher than 83.78% of the control group, the difference was statistically significant (P <0.05). Conclusion: The application of alprostadil injection in the clinical treatment of patients with acute cerebral infarction, help to quickly reduce the level of fibrinogen in patients and improve the overall efficiency of clinical treatment.