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目的探讨卡前列素氨丁三醇治疗产后出血的临床效果。方法选取2012年6月-2013年6月我院收治的139例剖宫产术中具有产后出血高危因素孕产妇,随机分为观察组69例和对照组70例,2组孕产妇均在腰硬联合麻醉下行子宫下段剖宫产术结束分娩,观察组在胎儿娩出后,于子宫肌内注射卡前列素氨丁三醇注射液;对照组孕妇胎儿娩出后于宫壁处注射缩宫素,比较2组效果。结果观察组产妇术中出血量、产后2h及24h出血量均明显少于对照组,产后出血发生率4.34%明显低于对照组的12.85%,2组比较差异有统计学意义(P<0.05)。结论缩宫素联合宫内注射卡前列素氨丁三醇,可明显降低产后出血的风险,能有效减少患者产后出血量,且用药安全、方便。
Objective To investigate the clinical effect of carboprost trometamol on postpartum hemorrhage. Methods From June 2012 to June 2013, 139 pregnant women with high risk factors for postpartum hemorrhage under cesarean section in our hospital were randomly divided into observation group (69 cases) and control group (70 cases). The two groups of pregnant women Hard joint anesthesia downstream uterine cesarean section at the end of childbirth, the observation group after the fetus was delivered intramuscularly intramuscular injection of carboprost tromethamine injection; control group of pregnant women after delivery of fetal uterine wall at the oxytocin injection, Compare 2 effects. Results The amount of bleeding in the observation group was significantly lower than that in the control group at 2h and 24h postpartum. The incidence of postpartum hemorrhage was 4.34%, which was significantly lower than that of the control group (12.85%), the difference was statistically significant (P <0.05) . Conclusion Oxytocin combined with intra-uterine injection of carboprost tromethamine can significantly reduce the risk of postpartum hemorrhage, can effectively reduce the amount of postpartum hemorrhage, and medication safe and convenient.