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目的:研究讨论甘精胰岛素联合阿卡波糖治疗老年糖尿病的临床疗效。方法:选择2013年3月-2014年9月在我院就诊的86例病例,随机将其分成两组,对照组单纯使用阿卡波糖治疗,观察组则使用甘精胰岛素联合阿卡波糖治疗。同时对比两组治疗前后的空腹血糖含量(FBG)、饭后2小时血糖含量(PBG)、糖化血红蛋白(HbAlC)三个指标,并对此进行分析比较。结果:对比分析患者治疗前后空腹血糖(FBG)、饭后2小时血糖(PBG)、糖化血红蛋白(HbAlC)三项指标,观察组患者使用药物后三项标准下降幅度均大于对照组,两组比较出现明显差异(P<0.05),存在统计学意义。经过两组疗效的对比可知,研究组治疗后显效有23例,有效有18例,总有效率是95.35%;对照组显效有12例,有效有22例,总有效率有79.07%。研究组的显效和总有效率高于对照组,存在明显差异(P<0.05),有统计学意义。结论:甘精胰岛素联合阿卡波糖治疗老年糖尿病能在短时间内平稳患者的血糖含量,更安全有效,值得临床推广。
Objective: To study the clinical effects of insulin glargine combined with acarbose in the treatment of senile diabetes mellitus. Methods: Totally 86 cases were treated in our hospital from March 2013 to September 2014 and randomly divided into two groups. The control group was treated with acarbose only. The observation group was given insulin glargine combined with acarbose treatment. The fasting blood glucose (FBG), postprandial blood glucose (PBG) and glycosylated hemoglobin (HbA1c) were compared between the two groups before and after treatment. Results: The fasting blood glucose (FBG), postprandial blood glucose (PBG) and hemoglobin A1c (HbA1c) were compared between the two groups before and after treatment. In the observation group, the decline of the three criteria after using the drugs was greater than that of the control group. There was a significant difference (P <0.05), there is statistical significance. After comparing the two groups of curative effects, we can see that there were 23 cases in study group and 18 cases in effective group. The total effective rate was 95.35%. In the control group, 12 cases were markedly effective and 22 cases were effective. The total effective rate was 79.07%. The effective rate and total effective rate of the study group were higher than that of the control group, there was a significant difference (P <0.05), with statistical significance. Conclusion: Glargine and acarbose treatment of elderly patients with diabetes mellitus in a short period of time to stabilize blood glucose levels, more safe and effective, worthy of clinical promotion.