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作者采用单式放射免疫弥散法测定系统性红斑狼疮(SLE)忠者血清中的C_3及C_4的蛋白量,并对其临床意义进行研讨。一.在SLE活动期C_3、C_4值:SLE活动期,特别是急性加剧期,C_3、C_4均减少,其中C_3减少更为显著,即在SLE活动期,C_3减少占其96％,C_4减少占其31％,而对照组的眼、口、生殖器三联症的活动期均一致上升,弥漫性硬皮病则在正常范围内。SLE活动期和非活动期C_3及C_4的测定,非活动期C_3全部上升,活动期和非活动期有统计学的显著意义;C_4在非活动期大部分病例显示上升,但无统计学意义。
The authors used monomeric radioimmunoassay to determine the amount of C_3 and C_4 proteins in the serum of loyal SLE patients, and its clinical significance was discussed. The value of C_3 and C_4 in SLE during active phase, especially acute exacerbation phase, decreased C_3 and C_4, and the decrease of C_3 was more significant, ie C_3 decreased by 96% and decreased by C_4 in SLE active phase The 31%, while the control group of eyes, mouth, genital triad activity period were consistently increased, diffuse scleroderma within the normal range. SLE activity and inactive C_3 and C_4 determination, inactive C_3 all increased, active and inactive periods were statistically significant; C_4 in most inactive cases showed an increase, but not statistically significant.