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目的:探讨99Tcm-硫化铼胶体在乳腺癌前哨淋巴结(SLN)活检中的应用价值。方法:30例T1～T2期乳腺恶性肿瘤患者入选,术前15～24 h乳晕下注射99Tcm-硫化铼,使用SPECT/CT进行SLN淋巴显像,定位;术中用γ探测仪寻找SLN,行SLN活检后,常规行乳癌手术;术后对SLN活检和腋窝淋巴结(ALN)清扫的病理结果进行比较分析。结果:30例共有29例检到SLN,共检出SLN 31枚,检出率,准确率分别为97.67%,100%;SLN状态与腋淋巴结转移的符合率为100%,无假阳性及假阴性情况出现。结论:99Tcm-硫化铼用于乳腺癌SLN活检是一种较理想的核素示踪剂。
Objective: To investigate the value of 99Tcm-rhenium sulfide colloid in the biopsy of sentinel lymph node (SLN) in breast cancer. Methods Thirty patients with T1 ~ T2 malignant breast cancer were enrolled. 99Tcm-rhenium sulfide was injected into the areola in 15-24 hours before operation, and SLN lymphoscintigraphy was performed using SPECT / CT. After SLN biopsy, routine breast cancer surgery was performed; postoperative pathological results of SLN biopsy and axillary lymph node (ALN) dissection were compared. Results: A total of 29 cases of SLN were detected in 30 cases, 31 SLNs were detected, the detection rate and accuracy were 97.67% and 100% respectively. The coincidence rate of SLN status and axillary lymph node metastasis was 100% Negative situation occurs. Conclusion: 99Tcm-rhenium sulfide is an ideal nuclide tracer for SLN biopsy of breast cancer.