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农用杀菌剂从十九世纪开始应用,二次世界大战后引入有机合成杀菌剂,二十世纪六十年代后,一些细胞分裂抑制剂,类脂合成抑制剂等所谓“作用点专一性抑制剂”陆续实用化,取代了以往的“多作用点抑制剂”。杀菌剂的这种发展无疑对防治病害起了很大作用,但另一方面也产生诸如“抗药性”等问题。同时,对杀菌剂的安全性也提出了更高的要求。在对待和解决这些问题的同时,要谋求杀菌剂向新的方向发展,以生物测定法为基础的杀菌剂试验方法的研究,
Since the 19th century, agricultural fungicides have been applied. After the Second World War, organic synthetic fungicides were introduced. Since the 1960s some so-called “point-specific inhibitors of cell division inhibitors and lipid synthesis inhibitors ”One after another practical, to replace the previous“ multi-point inhibitor. ” This development of fungicides has undoubtedly played a significant role in disease prevention and control, but on the other hand, problems such as “drug resistance” have also arisen. At the same time, the safety of fungicides also put forward higher requirements. In dealing with and solving these problems at the same time, we must strive for the development of new fungicides to bioassay-based fungicide test method research,