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通过对２３例发作间歇期偏头痛患者及２０名年龄、性别匹配的正常对照组血６－ｋｅｔｏ－ＰＧＦ１α（６－酮前列腺素Ｆ１α）和ＴＸＢ２（血栓素Ｂ２）含量的测定，发现偏头痛患者的６－ｋｅｔｏ－ＰＧＦ１α含量较对照组低（Ｐ＜０．０１），ＴＸＢ２含量则两者无差异。作者认为低水平的６－ｋｅｔｏ－ＰＧＦ１α是偏头痛的发作及复发的重要物质基础之一，而ＴＸＢ２则意义不大。
Through the determination of 6-keto-PGF1α (6-ketoprostaglandin F1α) and TXB2 (thromboxane B2) levels in 23 patients with intermittent migraine and 20 age-matched and normal-matched controls, it was found that migraineurs The content of 6-keto-PGF1α was lower than that of the control group (P <0.01), while the content of TXB2 was not different between the two groups. The author believes that low levels of 6-keto-PGF1α is one of the important material basis for the onset and recurrence of migraine, while TXB2 is of little significance.