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目的 :探讨血清铜蓝蛋白 (CER)及恶性肿瘤特异生长因子 (TSGF)对恶性肿瘤的诊断意义。方法 :同时测定 5 0例正常人及 13 0例恶性肿瘤血清中的CER及TSGF的含量。结果 :7组恶性肿瘤患者血清CER含量均较正常人明显增加 ,增多具有统计学意义 (P <0 .0 0 5 ) ,7组恶性肿瘤科学研究血清中TSGF的含量均较正常人明显增加 ,均具有统计学意义 (P <0 .0 5 ) ,CER与TSGF对恶性肿瘤的阳性率分别为 80 0 %与 81 1% ,诊断准确率均为 86 4% ,二者相似 ,与癌胚抗原CEA具有显著相关性。CER与TSGF对各种恶性肿瘤均有较高的检出率 ,若两者联合检测阳性率可上升到 92 2 %。结论 :CER与TSGF对恶性肿瘤的早期筛选均具有重要的意义 ,CER与TSGF联合检测优于单项检测。
Objective: To investigate the diagnostic value of serum ceruloplasmin (CER) and malignant tumor specific growth factor (TSGF) in malignant tumors. Methods: The serum levels of CER and TSGF in 50 normal individuals and 130 malignant tumors were determined simultaneously. Results: Serum levels of CER in the 7 groups of malignant tumors were significantly higher than those in normal controls (P <0.05). The levels of serum TSGF in 7 groups of malignant tumors were significantly higher than those in normal subjects, (P0.05). The positive rates of CER and TSGF on malignant tumors were 80 0% and 81 1%, respectively, and the diagnostic accuracy rates were 86 4%. Both of them were similar to carcinoembryonic antigen CEA has a significant correlation. CER and TSGF have higher detection rate for all kinds of malignant tumors, and the positive rate of the combination of them can rise to 92 2%. Conclusion: Both CER and TSGF have important significance in the early screening of malignant tumors. The combined detection of CER and TSGF is superior to single detection.