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本实验以体内、外相结合的研究方法,探讨了药用植物红景天提取物—红景天素对体外培养人胚肺二倍体成纤维细胞(2BS)和大鼠肝脏的影响,观察了红景天素对2BS细胞生长和增殖的影响,以及对大鼠肝脏细胞形态和组化改变和肝组织中过氧化脂质(LPO)与肝血清超氧化物歧化酶(SOD)的变化。实验结果是红景天素能促进2BS细胞生长和增殖,降低大鼠肝组织LPO及肝细胞内脂褐素含量及酸性磷酸酶活性(ACPase)。结果证明红景天素有延缓细胞老化抗退变作用。
In this experiment, the effects of the Rhodiola sachalinensis extract, a medicinal plant salidroside, on human embryonic lung diploid fibroblasts (2BS) and rat liver were investigated by combining in vitro and in vivo methods. Effects of salidroside on the growth and proliferation of 2BS cells, as well as changes in morphology and histochemistry of rat liver cells, and changes in lipid peroxidation (LPO) and serum superoxide dismutase (SOD) in liver tissue. The result of the experiment is that salidroside can promote the growth and proliferation of 2BS cells, and reduce the liver tissue LPO and lipofuscin content in liver cells and acid phosphatase activity (ACPase). The results prove that rhodiola has the effect of delaying cell aging and anti-degeneration.