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为了比较伴梗阻的结直肠癌(OCC)与单纯性结直肠癌(CC)的复发风险,并寻找伴梗阻结直肠癌的治疗模式,Cortet M等人采用精算法分析在勃艮第(法国)癌症登记处收集的结直肠癌患者的数据,以评估局部复发和远处转移的情况,并使用Cox模型进行多变量分析。结果发现,OCC和CC的5年累积局部复发率分别为14.2%和7.6%(P=0.003),且多变量分析结果显示,梗阻是局部复发的独立危险因素(HR:1.53;95%CI:1.01~2.34;P=0.047),患者的分期为晚期和年龄两因素会增加局部复发的风险;OCC组的5年累积远处转移率比CC组高(36.1%比23.1%,P<0.001)。由此可见,复发依然是
To compare the risk of recurrent colorectal cancer (OCC) with simple colorectal cancer (CC) with obstruction and to find treatment modalities for obstructive colorectal cancer, Cortet M et al. Used a refined algorithm to analyze the risk of recurrent colorectal cancer in Burgundy (France) Colorectal cancer data collected by the Cancer Registry to assess local recurrence and distant metastases and multivariate analysis using the Cox model. The 5-year cumulative local recurrence rates of OCC and CC were 14.2% and 7.6%, respectively (P = 0.003). Multivariate analysis showed that obstruction was an independent risk factor for local recurrence (HR 1.53; 95% CI: 1.01 ~ 2.34; P = 0.047). The patients with advanced stage and age increased the risk of local recurrence. The 5-year cumulative distant metastasis rate in OCC group was higher than that in CC group (36.1% vs. 23.1%, P <0.001) . Thus, the recurrence is still