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目的对镉（ＣｄＣｌ）诱导小鼠胚胎细胞１．５Ｇｙ６０Ｃｏγ射线的交叉适应性反应及时间效应进行了研究。方法小鼠于孕９天给予氯化镉（ｉｖ）后，分不同时间间隔给１．５Ｇｙ６０Ｃｏγ射线照射，孕１０天时进行胚胎细胞染色体制备。结果０．２５～２．０ｍｇ／ｋｇ剂量的镉能诱导胚胎细胞抗辐射的交叉适应性反应，而且与给镉后照射的时间间隔有密切关系，４小时已显示明显适应性反应，８小时达最高，１２，２４小时则产生协同作用。结论氯化镉可引起交叉适应性反应并与给镉后照射时间相关。
Objective To investigate the cross-reactivity and time effect of cadmium (CdCl) -induced 1.5Gy60Coγ-rays in mouse embryonic cells. Methods The mice were exposed to 1.5Gy60Coγ ray at different intervals after giving cadmium chloride (iv) at 9 days of gestation. The chromosomes of embryos were prepared at 10 days of gestation. Results Cadmium at a dose of 0.25-2.0 mg / kg could induce the cross-reactivity of embryonic cells against radiation and was closely related to the time interval after exposure to cadmium. At 4 hours, a significant adaptive response had been observed. After 8 hours The highest, 12,24 hours have a synergistic effect. Conclusions Cadmium chloride can cause cross-adaptability and is related to the irradiation time after cadmium exposure.