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①目的 探讨脐血清体外对急性白血病化疗后骨髓抑制期造血细胞增殖的影响。②方法 采用体外粒单细胞集落形成单位（ＣＦＵ－ＧＭ）培养法，观察正常成人血清和脐血清，对正常造血细胞和急性白血病化疗后抑制期骨髓造血细胞增殖的影响。③结果 脐血清组的正常骨髓ＣＦＵ－ＧＭ 产率明显高于成人血清组（ｔ＝ ６．９９３，Ｐ＜０．０１），脐血清组的白血病化疗后骨髓ＣＦＵ－ＧＭ 产率亦高于成人血清组（ｔ＝ ３．０６０，Ｐ＜ ０．０５）。④结论 脐血清体外能促进正常骨髓和白血病化疗后抑制期骨髓造血细胞的增殖。
①Objective To investigate the effects of umbilical cord serum on the proliferation of hematopoietic cells in the myelosuppressive stage after acute leukemia chemotherapy in vitro. Methods The CFU-GM culture method was used to observe the effect of normal adult serum and umbilical serum on the proliferation of hematopoietic cells in normal hematopoietic cells and acute leukemia patients after chemotherapy. Results The yield of CFU-GM in normal bone marrow of cord blood serum group was significantly higher than that of adult serum group (t = 6.993, P <0.01). The yield of bone marrow CFU-GM after cord blood serum treatment was also higher than that of adult Serum group (t = 3.060, P <0.05). ④ Conclusion Umbilical cord serum in vitro can promote normal bone marrow and leukemia chemotherapy inhibition of bone marrow hematopoietic cells proliferation.