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目的 探讨兔坐骨神经火器性震荡伤后腰段脊髓病理变化特点。方法 火器伤组投射物为 0 38g钢珠 ,装药量 0 65g,致伤靶点为兔右后肢外侧坐骨神经体表投影线中点 ,切割伤组在同一水平切断坐骨神经 ,分别于光电镜下观察伤后 1d、3d、1周、2周、4周和 1 2周时腰段脊髓的病理变化。结果 火器伤组可见腰段脊髓有小出血灶、神经元水肿、空泡样变以及神经元数量减少等变化 ,切割伤组则未见这些病理改变。结论 与切割伤组比较 ,火器伤组腰段脊髓损伤重 ,神经元存活数量显著减少。
Objective To investigate the pathological changes of lumbar spinal cord after firearm sciatic nerve firearm injury in rabbits. Methods Firearm injury group projection material is 0 38g steel ball, the amount of loading 0 65g, the target of injury to the right hind limb lateral sciatic nerve surface projection line midline, cut the wound group at the same level cut sciatic nerve, were observed under light microscope The pathological changes of lumbar spinal cord at 1 day, 3 days, 1 week, 2 weeks, 4 weeks and 12 weeks were observed. Results In the firearm group, there was a small hemorrhagic foci in the lumbar spinal cord, changes in neuron edema, vacuolar degeneration, and neuron number decrease. No changes were found in the wounds in the burn wound group. Conclusion Compared with the incision wound group, the spinal cord injury of the firearm wound group was heavier and the number of neurons was significantly decreased.