论文部分内容阅读
作者设计了一种屋内鼻变应原激发系统,可使花粉症患者暴露于已知花粉浓度的环境中进行试验。试验在190×156×96cm的密闭室内进行,由特殊的管道供应空气;花粉置于有孔的胶囊内,以空气驱动,使其缓慢释放。试验过程中不断取样,计算空气中的花粉数。试验证明30mg花粉用此法驱动30分钟可在空气中产生1000粒/m~3的花粉浓度。记录1秒钟经口呼出空气的最大量和0.5秒钟经鼻吸入空气的最大量前者用以测量暴露于花粉后肺功能的改变,后者用以测量鼻充血状态。在冬季对13名花粉症患者进行了试验,花粉浓度约1000粒/m~3,暴露30分钟,结果未发现鼻通气情况改变或出现鼻充血症状。2名患者在浓度增至9000粒/m~3、6名患者在浓度增至35000粒/m~3时出现反应;
The authors designed an intranasal nasal allergen excitation system that allows patients with hay fever to be tested in an environment exposed to known pollen concentrations. The test was carried out in a closed chamber of 190 × 156 × 96 cm with air supplied by a special tube. The pollen was placed in a perforated capsule and driven by air to slowly release it. Constant sampling during the test to calculate the number of pollen in the air. Test proved that 30mg pollen by this method for 30 minutes in the air can produce 1000 / m ~ 3 pollen concentration. Record the maximum amount of air expired in one second and the maximum amount of nasal inhaled air in 0.5 seconds. The former measures changes in lung function after exposure to pollen, and the latter measures nasal congestion. Thirteen patients with hay fever were tested in winter, with a pollen concentration of about 1000 capsules / m 3 exposed for 30 minutes. No change in nasal ventilation or nasal congestion was observed. Two patients in the concentration increased to 9000 / m ~ 3, 6 patients in the concentration increased to 35000 / m ~ 3 reaction;