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本文回顾性总结近10年来住院肝硬化患者526例与非肝硬化者405例胆结石的发病情况,结果表明肝硬化组与非肝硬化组胆结石的发病率分别为11.22％和3.95％。两组比较差异显著(P<0.01)。其中胆色素结石占61.9％。其原因可能与肝脏对胆红素代谢异常和慢性溶血有关。肝硬化患者伴有黄疸为62.5％,但仅有25.4％的患者发现肝内外胆管结石。提示黄疸常常由于肝细胞损害所致。肝硬化伴胆结石无症状占66％,可能与胆囊结石发生率高有关。
This article retrospectively reviewed the incidence of gallstone disease in 526 cases of non-cirrhotic patients and hospitalized patients with cirrhosis in recent 10 years. The results showed that the incidence of gallstones in cirrhosis and non-cirrhotic patients were 11.22% and 3.95% respectively. The difference between the two groups was significant (P <0.01). Pigmented stones which accounted for 61.9%. The reason may be related to abnormal liver bilirubin metabolism and chronic hemolysis. Cirrhosis patients with jaundice was 62.5%, but only 25.4% of patients found intrahepatic bile duct stones. Tip jaundice is often due to liver cell damage. Cirrhosis with gallstone asymptomatic 66%, may be related to the high incidence of gallstone.