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采用控制释药系统完全适用于避孕和医疗。应用此技术避孕可达到(1)不必每日用药;(2)妇女完全能自己用药;(3)对女性生殖器官靶位给予避孕药,可减少全身或局部副作用;(4)经组织靶位给药可减少全身性甾体激素的负荷量,以减少其致癌的可能性。目前设计避孕控制给药系统的方法有五种(参见表1)。本文将评述此五种方法的优缺点、避孕效果和副作用。一、每月用一次的注射剂尚未在全世界范围内生产和使用,近20年已有15个以上此类制剂进行临床试验,但
Controlled drug delivery system is completely suitable for contraception and medical treatment. Contraceptive use of this technology can be achieved (1) do not have daily medication; (2) the women can completely own medication; (3) the female reproductive organs target contraceptives, can reduce systemic or local side effects; (4) Administration reduces systemic load of steroid hormones to reduce their potential for carcinogenesis. There are currently five ways to design a contraceptive control delivery system (see Table 1). This article reviews the advantages and disadvantages of these five methods, their contraceptive effects and their side effects. First, once a month injections have not yet been produced and used around the world, over the past 20 years more than 15 such preparations for clinical trials, but