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急性心肌梗塞的医院死亡率主要是由血泵衰竭引起。在这些病人中曾用拟交感神经胺类药物治疗.去甲肾上腺素增加心肌收缩力,但产生强烈的周围和冠状动脉血管收缩,以致增加心肌氧耗量。异丙基肾上腺素是强有力的β-肾上腺能受体兴奋剂,但能使心率显著加速。多巴酚丁胺(Dobutamine)有增强心肌收缩力作用,但在心脏直视手术后病人中曾观察到有增加心率的作用。多巴胺能增加心肌收缩力,且能扩张肾动脉,但能产生室性心律失常.Prenalterol 是一新的选择性β_1-肾上腺素能受体兴奋剂,几乎无心率增速作用。本文报道 Prenalterol
The hospital mortality rate of acute myocardial infarction is mainly caused by blood pump failure. In these patients have been used to sympathomimetic amine therapy.Norepinephrine increases myocardial contractility, but produces strong peripheral and coronary vasoconstriction, resulting in increased myocardial oxygen consumption. Isoproterenol is a potent β-adrenergic receptor agonist, but can significantly accelerate heart rate. Dobutamine has an effect of enhancing myocardial contractility but has been shown to increase heart rate in patients after open heart surgery. Dopamine increases myocardial contractility and dilates the renal arteries, but produces ventricular arrhythmias.Prenalterol is a new, selective β 1 -adrenoceptor agonist with almost no heart rate acceleration. This article reports on Prenalterol