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目的观察布地奈德混悬液氧气驱动雾化吸入治疗新生儿毛细支气管炎的疗效。方法选2008年11月-2010年11月开封市儿童医院新生儿科收治的65例新生儿毛细支气管炎。随机分成对照组32例和观察组33例;入院后除均给予综合治疗外,观察组加用布地奈德混悬液氧气驱动雾化吸入治疗,疗程5~7 d。结果观察组治愈30例(90.9%),对照组为23例(71.9%),两组比较差异有统计学意义(χ2=3.91,P<0.05);在喘憋、哮鸣音、湿啰音、咳嗽消失方面差异有统计学意义(t=3.622,4.070,2.590,4.401,P<0.01、P<0.01、P<0.05、P<0.01)。结论布地奈德混悬液氧气驱动雾化吸入治疗新生儿毛细支气管炎临床疗效好,副作用小,使用安全。
Objective To observe the curative effect of inhalation of budesonide suspension by aerosol inhalation on neonatal bronchiolitis. Methods Selected from November 2008 - November 2010 Kaifeng City Children’s Hospital Neonatology 65 cases of neonatal bronchiolitis. Randomly divided into control group of 32 cases and observation group of 33 cases; except after admission were given comprehensive treatment, the observation group plus budesonide suspension oxygen inhalation therapy, treatment of 5 to 7 days. Results The observation group was cured in 30 cases (90.9%), the control group was 23 cases (71.9%), the difference between the two groups was statistically significant (χ2 = 3.91, P <0.05); wheezing, wheezing, , Cough disappeared (t = 3.622,4.070,2.590,4.401, P <0.01, P <0.01, P <0.05, P <0.01). Conclusion Budesonide suspension aerosol inhalation aerosol treatment of neonatal bronchiolitis with good clinical efficacy, side effects, safe to use.