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目的观察局部亚低温治疗高血压性脑出血患者的临床疗效。方法66例高血压性脑出血患者随机分为局部亚低温治疗组36例和对照组30例。在给予脑出血常规治疗的同时,局部亚低温治疗组加用局部亚低温治疗仪(电子冰帽)治疗。观察脑内血肿体积、血肿周围水肿体积及神经功能缺失评分的变化。结果入组后7d两组的血肿体积、血肿周围水肿体积及神经功能缺失评分差异无统计学意义。入组后14d时,局部亚低温治疗组颅内血肿体积(20.54±16.41ml)和对照组(22.26±13.20)ml相比,差异无统计学意义(P<0.05);血肿周围水肿体积(22.01±12.08)ml较对照组(28.21±10.02)ml有显著缩小;神经功能缺失评分(20.15±10.02)分亦较对照组(26.18±11.26)分有显著改善。结论电子冰帽局部亚低温治疗能促进高血压脑出血患者血肿周围水肿的消退,改善临床神经功能缺损。
Objective To observe the clinical efficacy of local mild hypothermia in patients with hypertensive intracerebral hemorrhage. Methods 66 patients with hypertensive intracerebral hemorrhage were randomly divided into local mild hypothermia treatment group 36 cases and control group 30 cases. In the given routine treatment of cerebral hemorrhage, local mild hypothermia treatment group plus local mild hypothermia treatment (electronic ice cap) treatment. Changes in intracerebral hematoma volume, edema volume around hematoma, and neurological deficit scores were observed. Results There was no significant difference in hematoma volume, volume of edema around the hematoma and neurological deficit score between the two groups on the 7th day. Compared with control group (22.26 ± 13.20) ml, there was no significant difference in the intracerebral hematoma volume (20.54 ± 16.41ml) between the local mild hypothermia group and the control group (P <0.05) ± 12.08) ml was significantly smaller than that of the control group (28.21 ± 10.02) ml. The neurological deficit score (20.15 ± 10.02) was also significantly improved compared with the control group (26.18 ± 11.26). Conclusion The local hypothermia treatment with electronic ice caps can promote the regression of edema around the hematoma in patients with hypertensive intracerebral hemorrhage and improve the clinical neurological deficits.