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目的探索出生缺陷危险因素,制定干预措施。方法对崇州市2000-2010年出生缺陷监测资半中进行分析。结果 11年间出生缺陷发生率为10.00‰,呈上升趋势,每年按4.48%速度递增。出生缺陷分类前5位依次为多指(趾)、唇(腭)裂、外耳及其他畸形、马蹄内外翻、外耳道闭锁,占出生缺陷总数的61.29%。缺陷儿死亡率(74.76‰)高于非缺陷儿死亡率(6.20‰)。在出生缺陷中,有7.28%的孕母在孕早期有患病、服药、接触有害物质等因素。出生缺陷产后临床诊断占81.31%,产前B超诊断占16.75%,结论针对出生缺陷发生的原因提出了婚前卫生指导、围产儿保健和送传咨询、提高产前诊断技术等干预措施。
Objective To explore the risk factors of birth defects and to make interventions. Methods The data of birth defects monitoring in Chongzhou from 2000 to 2010 were analyzed. Results The incidence of birth defects in 11 years was 10.00 ‰, showing an upward trend, increasing at an annual rate of 4.48%. The top five categories of birth defects were multi-finger, labial cleft, external ear and other malformations, internal and external horseshoe valgus, external auditory canal atresia, accounting for 61.29% of the total number of birth defects. Defective child mortality (74.76 ‰) is higher than non-defective child mortality (6.20 ‰). In birth defects, there are 7.28% of pregnant mothers in the first trimester of illness, medication, exposure to harmful substances and other factors. Postpartum clinical diagnosis of birth defects accounted for 81.31%, prenatal diagnosis of B-ultrasound accounted for 16.75% Conclusion pre-marital health guidance for prenatal birth defects, prenatal care and delivery advice, improve prenatal diagnosis techniques and other interventions.