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已报道血小板活化因子(PAF)在炎性反应中发挥作用。作者检测23例胸水患者中PAF,同时检测胸水中PAF 与中性粒细胞和(或)嗜酸细胞的关系。23例胸水患者,其基础疾病包括:9例气胸、2例结核性胸水、脓胸和肺水肿各3例、肺癌4例、慢性淋巴细胞性白血病和嗜酸细胞性肺炎各1例.所有患者均插胸腔导管,7～14天后收集24小时胸水,测定其PAF 含量.结果嗜酸细胞性肺炎、中性细胞浸润性气胸和脓胸患者胸水中,PAF 值分别为340fmol/ml,50～170fmol/ml 和1250～2130fmol/ml。结核性胸膜炎,肺水肿和肺癌或慢性淋巴细胞性白血病患者胸水中PAF 均≤10fmol/ml,但白细胞计数低,且以淋巴细胞为主。胸水中PAF 水平与中性白细胞和嗜酸
Platelet-activating factor (PAF) has been reported to play a role in the inflammatory response. The authors examined PAF in 23 patients with pleural effusion and examined the relationship between PAF in pleural fluid and neutrophils and / or eosinophils. Among the 23 patients with pleural effusion, the underlying conditions included 9 pneumothorax, 2 tuberculous pleural effusion, empyema and pulmonary edema in 3, lung cancer in 4, chronic lymphocytic leukemia and eosinophilic pneumonia in 1. All patients PAF were collected 24 hours after 7 ~ 14 days.Results The pleural effusion PAF in patients with eosinophilic pneumonia, neutrophilic infiltration pneumothorax and empyema were 340fmol / ml, 50 ~ 170fmol / ml and 1250 ~ 2130fmol / ml. Patients with tuberculous pleurisy, pulmonary edema and lung cancer or patients with chronic lymphocytic leukemia pleural fluid PAF were ≤ 10fmol / ml, but low white blood cell count, and mainly lymphocytes. Pleural effusion PAF levels and neutrophils and acidophilic