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目的探讨总结双期增强多排螺旋CT(multi-slice CT,MSCT)在胰腺神经内分泌肿瘤(neuroendocrine tumors,NET)的影像特征。方法 37例胰腺NET患者均行双期增强MSCT检查,观察不同分级患者肿瘤位置、肿瘤边界等影像特征,比较不同分级患者动脉期肿瘤相对最高强化程度(A1)、相对最低强化程度(A2),门静脉期肿瘤相对最高强化程度(V1)、相对最低强化程度(V2)。结果不同分级患者肿瘤位置、肿瘤边界、囊变/坏死及结节状钙化比例比较差异均无统计学意义(P>0.05);3级患者A1[(36.2±9.4)Hu]、A2[(22.4±13.5)Hu]、V1[(41.4±6.3)Hu]、V2[(34.6±6.2)Hu]明显低于1级[A1为(128.7±39.5)Hu,A2为(93.9±28.5)Hu,V1为(70.1±12.5)Hu,V2为(63.2±17.4)Hu]、2级患者[A1为(78.7±38.6)Hu,A2为(62.7±31.7)Hu,V1为(69.3±10.7)Hu,V2为(62.5±10.8)Hu](P<0.05);2级患者A1、A2明显低于1级患者(P<0.05),V1、V2与1级患者比较差异无统计学意义(P>0.05)。结论双期增强MSCT有助于胰腺NET的诊断,辅助判断术前肿瘤恶性程度。
Objective To investigate the imaging features of multi-slice CT (MSCT) in pancreatic neuroendocrine tumors (NET). Methods 37 patients with pancreatic NET were examined by double-phase enhanced MSCT. The tumor location and tumor boundary were observed in different grading patients. The relative maximum enhancement (A1), relative minimum enhancement (A2) The relative maximum degree of portal vein tumor enhancement (V1), the relative minimum degree of enhancement (V2). Results There was no significant difference in the tumor location, tumor border, cystic / necrosis and nodular calcification between the different grading patients (P> 0.05). Grade 3 A1 [(36.2 ± 9.4) Hu, V1 [(41.4 ± 6.3) Hu] and V2 [(34.6 ± 6.2) Hu] were significantly lower than Grade 1 [A1 was (128.7 ± 39.5) Hu and A2 was (93.9 ± 28.5) (70.1 ± 12.5) Hu, and V2 was (63.2 ± 17.4) Hu. Patients in grade 2 [A1 was (78.7 ± 38.6) Hu, A2 was (62.7 ± 31.7) Hu and V1 was (69.3 ± 10.7) (62.5 ± 10.8) Hu] (P <0.05). The level of A1 and A2 in grade 2 patients was significantly lower than that in grade 1 patients (P <0.05). There was no significant difference in grade 1, . Conclusions Double-phase enhanced MSCT is helpful for the diagnosis of pancreatic NET, and helps to determine the degree of preoperative tumor malignancy.