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目的通过应用经胸二维超声检查来观察冠状动脉硬化（coronary atherosclerosis, CAS）在正常人群中的发生率，探讨年龄因素与CAS发病率和程度的关系。方法选择无高血压、糖尿病、高血脂、无冠心病临床表现和心电图异常的正常人71例，按照年龄分成青中老年三组，应用经胸超声检查冠状动脉，确定有无CAS。结果经胸超声检查正常人群中CAS总检出率为40.8%，青、中、老年组CAS检出率分别为：13.8%，42.9%和92.9%，随年龄增长而增高，各年龄组之间CAS检出率有统计学差异（P<0.05）。老年组CAS程度和范围增加。结论年龄在正常人群中是CAS的主要影响因素之一。超声检查能为冠心病的诊断提供有价值的临床信息。“,” Objective To evaluate the positive rate of inspecting coronary atherosclerosis(CAS) in normal persons and explore the correlation between ages and percentage of patients with CAS and extends of CAS by transthoracic echocardiography (TTE).Methods 71 normal persons, no high blood pressure, diabetes mel itus hypercholesterolemia, no clinical manifestation of coronary heart disease no ECG abnormality, were divided into three groups according to ages, young, middle old age groups. TTE was applied to examine and ascertain whether there being CAS or not.Results CAS was visualized 40.8% of al the normal persons by TTE. The positive rate of detecting CAS was 13.8%, 42.9% and 92.9% respectively in young, middle and old age groups . The positive rate increased with the age. There was statistical difference in the positive rate of CAS among the three groups(P<0.05).The degrees and extension of CAS in senility group increased remarkably. Conclusions Age was one of the primary effecting factors of CAS TTE can afford valuable information for the diagnosis of CAS.