论文部分内容阅读
作者研究了66例慢性活动肝炎(CAH)患者的致病环境因子(如病毒和药物)的发生率。22例(33%)患者具有符合病毒性肝炎的肝脏组织学改变,并在嗣后检时发展为慢性侵袭性肝炎,或者在发生症状时血清中有乙型肝炎表面抗原(HBsAg)。其余44例中有22例血清中有可检出的抗甲型肝炎病毒的抗体,表明有接触甲型肝炎病毒(HAV)的证据。然而这个发生率并不明显大于一组健康对照者中的发生率,因此,在本研究材料中,HAV在CAH的发生中似无意义。2例CAH患者可能由非甲非乙型肝炎所致,因为这2例最初有急性病毒性肝炎的组织学改变,但HAV和乙型肝炎病毒(HBV)的血清学标志缺如。17例
The authors studied the incidence of pathogenic environmental factors (such as viruses and drugs) in 66 patients with chronic active hepatitis (CAH). Twenty-two patients (33%) had liver histological changes that corresponded to viral hepatitis and progressed to chronic invasive hepatitis at later seizures or hepatitis B surface antigen (HBsAg) in sera when symptoms occurred. Of the remaining 44 cases, 22 had detectable antibodies against hepatitis A virus in serum, indicating evidence of exposure to the hepatitis A virus (HAV). However, this incidence was not significantly greater than in a group of healthy controls, so HAV appears to be meaningless in CAH in this study. Two patients with CAH may be due to non-A, non-B hepatitis, as these two initially had histological changes in acute viral hepatitis, but serological markers of HAV and Hepatitis B virus (HBV) were absent. 17 cases