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在日本可以认为妊妇贫血几乎都由缺铁引起,而大红细胞性贫血罕见,在欧美则大红细胞性贫血的发病率较高。为寻求两者为何各异,作者测定100名日本人妊妇血中的叶酸值,在妊娠经过中均见下降,平均值在妊娠36周时为5.4毫微克/毫升,分娩后1月为5.3毫微克/毫升。血清铁在妊娠经过中也均下降,于分娩后恢复正常。血清铁和血中叶酸值的关系是,在妊娠36周时仅血清铁下降的有32％;两者同时下降的有42％。然而贫血多为小细胞低色素型贫血,因叶酸缺乏全被缺铁所遮盖,放无1例呈大红细胞性贫血。作者任意选择妊娠28周的门诊产妇100例,分为两组,一组予铁剂(48.5毫克/日),另一组予铁剂
Almost all anemia in pregnant women in Japan can be caused by iron deficiency, and rare erythroblastic anemia in Europe and the United States is the incidence of erythrocytic anemia. To find out why the two differed, the authors determined that folic acid levels in maternal blood of 100 Japanese women decreased throughout pregnancy, with an average of 5.4 ng / mL at 36 weeks of gestation and 5.3 after delivery Ng / ml. Serum iron also decreased during pregnancy and returned to normal after childbirth. The relationship between serum iron and blood folic acid was that there was only 32% decrease in serum iron at 36 weeks of gestation; both decreased by 42% at the same time. However, anemia mostly small cell hypochromic anemia, due to lack of folic acid were all covered by iron deficiency, put no case of erythrocytic anemia. The author randomly selects 100 outpatients during the 28 weeks of gestation and is divided into two groups: one is iron (48.5 mg / day) and the other is iron