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L 苯丙氨酸 (L Phe)是医药输液制品和食品添加剂APM (健康糖 )的必需成分 ,全球每年需求量为 3万t,主要由美国孟山都公司、日本味之素公司、韩国大象公司、德国迪高萨公司等几家大公司生产 ,我国 1998年以前所需要的L Phe全部依靠进口。中国科学院成都生物研究所于 1991年成功开发了红酵母苯丙氨酸解氨酶 (PAL) /肉桂酸技术途径生产L Phe,并于 1998年与企业合作建成了一套 10 0t/a生产装置 ,使得我国成为继美、日、德、韩之后又一个能够工业化生产这一重要氨基酸产品并自主开发这一高新技术的国家。目前 ,我国L Phe的实际产量只有 5 0 0～ 6 0 0t/a ,进口量达 70 0t/a ,因此 ,未来L Phe发展前景看好。
L Phenylalanine (L Phe) is an essential component of pharmaceutical infusion products and food additives APM (health sugar), the global annual demand of 30000 t, mainly by the United States Monsanto, Japan’s Ajinomoto Corporation, the Korean elephant company , Germany Di Gao Sa several large companies such as production, China before 1998 required L Phe all rely on imports. Chengdu Institute of Biology, Chinese Academy of Sciences, successfully developed Lphe by means of PAL / Cinnamic acid technology in 1991 and established a set of 10 t / a production plant in cooperation with the enterprises in 1998 , Making our country another country that can industrially produce this important amino acid product after the United States, Japan, Germany and South Korea and independently develop this high-tech product. At present, the actual output of L Phe in our country is only 500 ~ 600t / a and the import volume is 70 0t / a. Therefore, the future development of L Phe is promising.