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目的探讨唐山市部分中老年干部人群中代谢综合征的发病率及血清尿酸水平与代谢综合征危险因素的关系,为代谢综合症合并高尿酸血症的防治提供科学依据。方法选取2010年在迁安市老干部局医院参加健康体检的50岁以上离退休人员共2351人作为研究对象。专人采集病史,同时按统一方法测量血压、身高、体重、腰围、臀围等,并检验血尿酸、血糖、血脂等生化指标。结果体检人群代谢综合征患病率为27.6%(640/2321);男性患病率为25.9%,女性为30.3%;各种组分患病率依次为高血压﹥高血糖﹥超重肥胖﹥高血脂;平均血尿酸水平为(322.21±79.70)mg/L,其中男性尿酸水平为(338.07±78.26)mg/L,女性为(295.26±74.76)mg/L;高尿酸血症患病率为11.7%(271/2321),男性为14.0%,女性为7.7%;血尿酸水平与代谢综合征的多元Logistic回归分析显示:男性高尿酸血症人群患代谢综合征的风险为血尿酸正常人群的1.853倍;女性高尿酸血症人群患代谢综合征的风险为血尿酸正常人群的2.838倍。结论血尿酸水平的升高增加了代谢综合征发生的风险。
Objective To investigate the incidence of metabolic syndrome and the relationship between serum uric acid level and risk factors of metabolic syndrome in some middle-aged and elderly cadres in Tangshan city, and to provide scientific evidence for the prevention and treatment of metabolic syndrome combined with hyperuricemia. Methods A total of 2351 retired people over the age of 50 who participated in the health examination in the cadres Bureau Hospital of Qian’an City in 2010 were selected as the research object. Personal history, at the same time according to a unified method of measuring blood pressure, height, weight, waist circumference, hip circumference, and test blood uric acid, blood glucose, blood lipids and other biochemical indicators. Results The prevalence of metabolic syndrome was 27.6% (640/2321) in the physical examination population. The prevalence rate was 25.9% in males and 30.3% in females. The prevalence rates of various components were hypertension, hyperglycemia, and overweight and obesity (322.21 ± 79.70) mg / L, the male uric acid level was (338.07 ± 78.26) mg / L and the female was (295.26 ± 74.76) mg / L; the prevalence of hyperuricemia was 11.7 % (271/2321), 14.0% in males and 7.7% in females. Multivariate logistic regression analysis of serum uric acid levels and metabolic syndrome showed that the risk of metabolic syndrome in male patients with hyperuricemia was 1.853 Times; women with hyperuricemia risk of metabolic syndrome in patients with normal uric acid 2.838 times the normal population. Conclusion Increased serum uric acid levels increase the risk of metabolic syndrome.