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对５４２例肝硬化并发食管静脉曲张患者行硬化剂治疗，随访１～７年，平均为３．９年。按所用硬化剂不同分四组：（１）５％鱼肝油酸钠８１例；（２）纯酒精６７例；（３）混合剂（鱼肝油酸钠加纯酒精）２０９例；（４）混合剂加服汉防己甲素１８５例。结果：急性出血止血率９５．５％，曲张静脉消失率１２１例（２２．３％），完全消失仅２２例。止血效果四组间无差异。静脉曲张消失以３、４组为高（Ｐ＜０．０５）。失访２３例，改外科治疗７０例。累计再出血率为１４．７％，死亡９５例，占随访４４９例２１．１％。直接死于再发出血３４例。随访期生存例数３５４例（７８．８％）。本文提示硬化剂治疗食管静脉曲张急性出血止血率高，但曲张静脉消失率仍低，若加服汉防己甲素并结合外科治疗能提高病人生存率。
542 cases of cirrhosis complicated with esophageal varices in patients with sclerotherapy, followed up for 1 to 7 years, an average of 3.9 years. According to the different hardeners divided into four groups: (1) 5% sodium cod liver oil in 81 cases; (2) 67 cases of pure alcohol; (3) mixture of cod liver oil and pure alcohol) 209; Serve a total of 185 cases of tetrandrine. Results: The hemostasis rate of acute hemorrhage was 95.5%, and the disappearance rate of varicose veins was 121 (22.3%). Only 22 cases disappeared completely. Hemostatic effect no difference between the four groups. Varicose veins disappeared in 3,4 groups were higher (P <0.05). Lost in 23 cases, surgical treatment of 70 cases. The cumulative rebleeding rate was 14.7%, with 95 deaths, accounting for 21.1% of 449 follow-up visits. Directly died of recurrence of bleeding in 34 cases. The number of surviving cases at follow-up was 354 (78.8%). This article suggests that the hardener treatment of esophageal variceal hemorrhage bleeding rate, but varicose vein disappearance rate is still low, if combined with tetrandrine and surgical treatment can improve patient survival.