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选符合诊断标准的急性胰腺炎患者 62例 ,随机分为中西医结合治疗组与西医治疗对照组各 3 1例。治疗组予生大黄结合西医综合疗法 ,对照组仅用西医疗法。结果 :治疗组痊愈 19例 ,显效 9例 ,有效 2例 ,无效 1例 ,总有效率为 96.8%( 95 % CI=83 .3 %～ 99.9% ) ;对照组痊愈 4例 ,显效 6例 ,有效 10例 ,无效 11例 ,总有效率为 64 .5 % ( 95 % CI=45 .4%～80 .8% ) ;治疗组综合疗效明显优于对照组 ( u=4.5 988,P<0 .0 0 0 1) ;且两组 95 %的可信区间不重叠 ;治疗组发生无效患者的危险性明显降低 ( OR=0 .0 6,95 % CI=0 .0 1～ 0 .5 1) ;治疗组每治疗 3人 ,可较对照组减少 1例无效患者 ( NNT=3 ,95 % CI=1.93～ 7.95 )
Sixty-two patients with acute pancreatitis who meet the diagnostic criteria were randomly divided into three groups: 31 cases in combination with western medicine and western medicine. The treatment group was given rhubarb combined with western medicine combined therapy, the control group only Western medical treatment. Results: The treatment group cured 19 cases, 9 cases markedly effective, 2 cases effective, 1 case ineffective, the total effective rate was 96.8% (95% CI = 83.3% ~ 99.9%); the control group recovered in 4 cases, markedly effective in 6 cases, The total effective rate was 64.5% (95% CI = 45.4% -80.8%). The curative effect of the treatment group was obviously better than that of the control group (u = 4.5988, P <0) .0 0 0 1); 95% confidence intervals of the two groups did not overlap; the risk of patients with ineffective treatment was significantly lower (OR = 0.60,95% CI = 0.01-0.51 ). One invalid patient (NNT = 3, 95% CI = 1.93 ~ 7.95) was reduced in treatment group compared with control group for every 3 patients.