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扭曲(twist)基因属于碱性螺旋-环-螺旋蛋白家族中高度保守的转录因子,在胚胎的发生发展中发挥着重要的作用。下文就扭曲基因的结构特征、与之表达相关的调控机制及其在牙髓干细胞中所起的作用作一综述。
The twist gene is a highly conserved transcription factor in the basic helix-loop-helix protein family and plays an important role in the development of embryos. The following text reviews the structural features of distorted genes, the regulatory mechanisms involved in their expression, and their roles in dental pulp stem cells.