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许多有机锑衍生物对若干寄生虫病(例如血吸虫病、丝虫病、黑热病等)有一定疗效,但因对人体毒性较高,临床使用每多顧虑.近年来药物化学研究常着眼在找寻新药以代替这些锑化合物.锡化合物向来很少用作医药制剂,但近年来报导一氧化锡能治疗肠血吸虫病,二丁基锡盐是鸡肠寄生虫病的有效药剂,Kerk及Luijten更曾系统地试验了他们所合成的许多锡有机化合物,找到其中若干系列具有强烈的抑制霉菌或杀虫作用,并且这些物质对热血动物不一定有高度毒性。
Many organic antimony derivatives have some curative effect on several parasitic diseases (such as schistosomiasis, filariasis, kala-azar, etc.), but they are often considered in clinical use due to their high toxicity to human beings. In recent years, New drugs to replace these antimony compounds. Tin compounds have always been seldom used for pharmaceutical preparations, but in recent years reported that tin oxide can treat intestinal schistosomiasis, dibutyltin salt is an effective agent for chicken intestinal parasites, Kerk and Luijten more systematically Many of the tin compounds they have synthesized were tested and several of them were found to have a strong inhibitory effect on mold or insecticide and these substances are not necessarily highly toxic to warm blooded animals.