Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers

• 作 者: You-Kyung Jeon Sung-Hee Kim Se
• 机 构: LaboratoryofCellBiologyCancer,ColorectalCancerBranch
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2010年25期
• 基金项目: Supported by (in part) The Korea Science and Engineering Foundation (KOSEF) funded by the Korean government (MEST R01-2008-000-20108-0)

AIM: To understand CD133 promoter hypermethyl-ation and expression in 32 colorectal cancer cell lines. METHODS: Nucleic acid was isolated from 32 colorectal cancer cell lines and CD133 expression levels were measured by reverse transcription-polymerase ch