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破碎QRS波在常规12导联心电图上表现为QRS波中出现额外的形态各异棘波，曾作为陈旧性心肌梗死的心电图诊断标志。然而，最近的研究已经将破碎QRS波的预警功能扩展到各种心血管疾病。侧重综述破碎QRS波与病理性Q波、QRS间期、心室晚电位的比较研究，并重点叙述了破碎QRS波所预示的心肌组织病理改变和心室血流动力学异常尤其心室内非同步收缩在诊断心血管疾病、判定预后以及在心脏再同步治疗决策中的应用潜能。“,”Fragmented QRS complex is defined as additional spikes within the QRS complex, and is evaluated by a 12-lead electro-cardiogram recording.Previous studies have demonstrated that the fragmented QRS complex used to be a marker of a prior myocardial infarc-tion.Whereas, recent evidence suggests that a fragmented QRS complex may be useful in the identification of a diagnosis, as well as predic-ting a prognosis, in various cardiovascular diseases.This review compares the different causative mechanisms of pathologic Q wave, QRS du-ration and late potentials with the fragmented QRS complex.It also examines the pathologic changes and hemodynamic abnormality of the heart at the time when patients have had the fragmented QRS complex detected on 12-lead electrocardiogram.