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本文作者报道百日咳菌苗不仅是一种降血糖剂,而且对动物有明显延长出血时间和血凝时间的作用.同时,对血小板的聚集作用也有影响.作者认为这些作用与百日咳菌苗的降低血糖的作用相关,并认为血小板聚集作用失调是由β肾上腺素能受体被阻断所引起.用百日咳菌苗分别对大鼠、家兔和狗进行腹腔内注射.注射后4、6天和8天后用Duke法测定大鼠出血时间.注射后第4天开
The authors report that pertussis vaccine is not only a hypoglycemic agent, but also significantly prolongs the bleeding time and hemagglutination time for animals. At the same time, it also has an impact on platelet aggregation. The authors believe that these effects and pertussis vaccines reduce blood sugar. The effects are related, and it is thought that the disorder of platelet aggregation is caused by the blockage of beta-adrenergic receptors. Rats, rabbits and dogs are injected intraperitoneally with pertussis vaccines. 4, 6, and 8 days after injection. Days later, the bleeding time of the rat was measured by the Duke method. It was opened on the 4th day after the injection.