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最后区(AP)位于脊髓中央管与第四脑室的移行部位,是机体的一个重要室周器官,具有感受化学性刺激、调节血压、参与呕吐反射及脑-脑脊液间信息交换等多种功能.免疫组织化学研究已证明大鼠最后区内有含有脑啡肽、P物质、胆囊收缩素、神经肽Y、神经降压肽等的神经肽能细胞或纤维终末.但最后区是否存在生长抑素样免疫反应阳性神经元,特别是从分子水平研究生长抑素mRNA(SOMmRNA)阳性细胞尚未见报道,而阐明这一问题可以为进一步探讨和解释最后区的生理机能提供新的形态学资料.
The last zone (AP) is located in the central part of the spinal cord and the fourth ventricle of the transitional part of the body is an important ventricular organ, with the feeling of chemical stimulation, regulate blood pressure, involved in vomiting reflex and brain - cerebrospinal fluid exchange of information and other functions. Immunohistochemical studies have shown that in the final region of rat there are neuropeptide cells or fibronectin containing enkephalin, substance P, cholecystokinin, neuropeptide Y, neurotensin, etc. However, in the last region, is there growth inhibition The immunoreactive positive neurons, especially the study of somatostatin mRNA (SOM mRNA) positive cells at the molecular level, have not been reported yet. To elucidate this problem may provide new morphological data for further exploring and explaining the physiological functions of the last region.