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应用免疫组代ABC法对75例良性前列腺增生（BPH）的组织中ER、AR及PR进行检测．结果显示ER、AR、PR在腺体和间质中均有分布，三种性激素受体在间质中的阳性率、含量和强度均高于腺体中，其差异有显著性（P＜0．05），表明性激素受体（SR）在间质中的效应作用在前列腺增生的发病机理中起了重要作用．笔者还发现ER随着年龄增长而有递增的趋势，而AR随着年龄有递减趋势．
Immunohistochemistry was used to detect ER, AR and PR in 75 cases of benign prostatic hyperplasia (BPH). The results showed that ER, AR and PR were distributed in the gland and stroma. The positive rates, contents and intensities of the three sex hormone receptors in the stroma were significantly higher than those in the gland (P <0 .05), indicating that the effect of the sex hormone receptor (SR) in the stroma plays an important role in the pathogenesis of benign prostatic hyperplasia. The author also found that ER has an increasing trend with age, while AR decreases with age.