论文部分内容阅读
目的:了解儿童万古霉素临床应用情况,并分析其临床用药的合理性。方法:回顾性分析2014年1月至2014年6月278例住院患儿使用万古霉素病情记录。结果:278例病例中,微生物送检率为96.4%,按药敏结果选择用药率为43.2%,以抗感染治疗性用药为主,用药方案以二联用药为主。用药合理及基本合理共111例(39.9%)。结论:我院在万古霉素的使用上存在不合理情况,针对临床应用万古霉素存在的问题,应建立特殊使用级抗菌药的限制性措施,严格控制用药指征,减少经验用药,有助于提高万古霉素的治疗效果及合理用药水平。
Objective: To understand the clinical application of vancomycin in children and to analyze the rationality of its clinical use. Methods: A retrospective analysis of 278 hospitalized children with vancomycin during January 2014 to June 2014 was performed. Results: In 278 cases, the detection rate of microbe was 96.4%. The drug selection rate was 43.2% according to the result of drug susceptibility. The anti-infective therapeutic drug was the main drug. A total of 111 cases (39.9%) were rational and reasonable. Conclusion: There is unreasonable use of vancomycin in our hospital. For the problems of clinical application of vancomycin, restrictive measures should be established for the use of special grade antibacterials. Strict control of drug indications and reduction of experience medication are helpful To improve the therapeutic effect of vancomycin and reasonable drug levels.