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目的通过描述布加氏综合征(Budd-Chiari syndrome,BCS)在人群及地区上的流行与分布状况,分析该病发病的危险因素,为预防疾病发生、防止疾病发展提供决策依据和方法。方法整理2004-2009年在徐州各家三级医院介入科住院治疗的578例BCS患者的基本资料,包括民族、性别、年龄、职业、血型、居住地区等,对男女性别比进行χ2检验;对男女年龄分布进行两样本t检验;进行职业分布图的绘制;血型分布与一般人群进行χ2检验比较;对病例居住地区在地图上标点。结果患者中99%为汉族,年龄集中于35~55岁的中青年,职业多为农民兼职打工者;通过患者与一般人群血型分布的比较得出:与其他血型相比较,O型血的人更不容易患上此病;病例集中分布于苏北、皖北等外环境高碘地区;徐州市204人中,有48%的患者(98例)居住于高速公路这种空气高度污染的环境中。结论我国布加氏综合征与体力劳动、血型基因、居住环境等因素密切相关,应该加强在这些方面研究的力度。积极做好疾病相关危险因素的干预工作,对高危人群进行必要的指导教育、健康保护与健康促进,采取必要的预防措施,降低疾病发生率。
OBJECTIVE: To describe the prevalence and distribution of Budd-Chiari syndrome (BCS) in human beings and regions, and to analyze the risk factors of Budd-Chiari syndrome (BCS) in order to prevent the occurrence of diseases and prevent the development of diseases. Methods The data of 578 BCS patients admitted to the tertiary hospitals in Xuzhou from 2004 to 2009 were analyzed, including the ethnicity, sex, age, occupation, blood type and living area, and the χ2 test was performed on the sex ratio of men and women. Male and female age distribution of two-sample t-test; occupation mapping drawing; blood group distribution and the general population χ2 test comparison; cases of living area punctuation on the map. Results 99% of the patients were Han nationality, middle-aged and young people aged 35-55 years. Most occupations were part-time migrant workers. Comparing the blood type distribution between the patients and the general population, we found that compared with other blood types, Less susceptible to the disease; cases concentrated in northern Jiangsu, northern Anhui and other high-iodine areas outside the environment; Xuzhou City, 204 people, 48% of patients (98 cases) living in the highway this air is highly polluted environment in. Conclusion The incidence of Budd-Chiari syndrome in China is closely related to physical labor, blood type genes, living environment and other factors, and research efforts in these areas should be strengthened. Actively do a good job of disease-related interventions in risk factors for high-risk groups for the necessary guidance and education, health protection and health promotion, to take the necessary precautions to reduce the incidence of the disease.