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肺淀粉样变是一种较少见的疾病,对于其临床与X线表现缺乏特异性,因此极易与肺部慢性感染或肿瘤相混淆而造成误诊。有报道30例肺淀粉样变仅有4例于生前作出诊断。多数须经病理学检查才能确诊,国内仅见周氏等报道一例经光束镜活检而证实,我院经剖胸肺活检及手术切除各1例经病理切片检查证实,本文结合文献复习加以讨论。【病因与发病机理】淀粉样变物质是一种无定形、嗜酸性、能对抗蛋白酶消化的一种蛋白质,为硫酸软骨素与大量丙种球蛋白的复合物,高度纯化的淀粉
Pulmonary amyloidosis is a rare disease characterized by a lack of specificity for clinical and radiological manifestations and is therefore easily misdiagnosed as a chronic lung infection or tumor. It has been reported in 30 cases of pulmonary amyloidosis only 4 cases in life to make a diagnosis. Most of the pathological examination to be diagnosed by the domestic only see Zhou and other reports of a case confirmed by beam microscopy and biopsy in our hospital by thoracic and lung biopsy and surgical resection in 1 case confirmed by biopsy, the paper reviewed in the literature to be discussed. Etiology and pathogenesis Amyloidosis is an amorphous, eosinophilic protein that is resistant to protease digestion. It is a complex of chondroitin sulfate with a large amount of gamma globulin, a highly purified starch