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高密度脂蛋白是血浆中的微粒,按重量计,脂质约占50%,载脂蛋白约占50%。脂质的主要成份是磷酯40～50%,胆固醇32%,甘油三酯10%;蛋白的主要成份为载脂蛋白 A-Ⅰ 65%,载脂蛋白 A-Ⅱ30%。近来的研究表明载脂蛋白可用于检出心肌梗塞的存活者。本研究试图确定载脂蛋白 A-Ⅰ作为识别心血管造影确定的冠状动脉病变的指标是否优于高密度脂蛋白(HDL)胆固醇以及载脂蛋白 A-Ⅰ水平是否与病变范围相关。方法:108例因胸痛或疑有冠心病而作了冠状
High-density lipoproteins are microparticles in plasma, accounting for about 50% by weight of lipids and about 50% by apolipoproteins. The major components of the lipid are 40-50% of phospholipids, 32% of cholesterol and 10% of triglycerides. The main components of the protein are apolipoprotein A-I 65% and apolipoprotein A-II 30%. Recent studies have shown that apolipoprotein can be used to detect myocardial infarction survivors. This study sought to determine if apolipoprotein A-I as a marker of coronary artery disease identified by cardiovascular angiography is superior to high-density lipoprotein (HDL) cholesterol and whether apolipoprotein A-I levels correlate with the extent of the disease. Methods: 108 cases of coronary heart disease due to chest pain or suspected