急性脑卒中患者血清铜锌镁测定的临床意义

• 作 者: 李春盛 蒋瑞英 李云琴 宋淑珍 郭玉茹 赵秀玲 单巍松 冯秀英
• 机 构: 北京部队总医院急诊科,北京部队总医院急诊科,北京部队总医院急诊科,北京部队总医院急诊科,北京部队总医院小儿科,北京部队总医院小儿科,北京部队总医院小儿科,北京部队总医院小儿科
• 出 处: 中国急救医学
• 发表日期: 1991年04期
• 关键词: 急性脑卒中 血清铜 脑梗塞组 脑血管病 鉴别诊断 血清微量元素 心肌受损 磷酸激酶 乙炔流量 脑水肿

本文应用原子吸收光谱法测定了急性脑卒中患者血清中的铜锌镁的浓度及铜锌比值与正常对照组相比,结果表明:急性脑卒中患者无论是脑出血或脑梗塞均表现为血清铜升高,锌镁降低,铜锌比值升高(p<0.001),而脑梗塞与脑出血组相比,脑出血组血清铜升高较脑梗塞组更为明显(p<0.01),因而铜/锌比值也有意义地升高(p<0.01),但锌镁均无明显改变,其结果可有助于二者的鉴别诊断。

In this paper, the concentrations of Cu, Zn and Mg in serum of patients with acute stroke were measured by atomic absorption spectrometry and the ratio of Cu / Zn was compared with that of the normal control group. The results showed that both acute cerebral apoplexy patients showed cerebral hemorrhage or cerebral infarction (P <0.001). Compared with cerebral hemorrhage group, the serum copper level in cerebral hemorrhage group was significantly higher than that in cerebral infarction group (p <0.01), and the content of copper / Zinc ratio also increased significantly (p <0.01), but no significant changes in zinc and magnesium, the results can contribute to the differential diagnosis of the two.